PCR for capsular typing of Haemophilus influenzae

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Real-time PCR for determining capsular serotypes of Haemophilus influenzae.

A two-step real-time PCR assay targeting all six capsulation loci of Haemophilus influenzae (i.e., serotypes a to f) was developed and compared with a previously published qualitative PCR assay by using 131 H. influenzae clinical isolates. There was a 98.5% concordance between the two tests. The sensitivity of detection of capsular type-specific reference strains of H. influenzae a to c (10(1) ...

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Measurement of Antibodies Reacting with Capsular Antigens of Haemophilus Influenzae.

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Haemophilus Influenzae B

  یکی از شایع ترین مننژیت باکتریایی در شیرخواران، هموفیلوس آنفلوانزا از نوع B (HIB) می باشد. به منظور تهیه و عرضه واکسنی جهت حفظ کودکان در مقابل این بیماری به بازار جهانی، تحقیقاتی انجام و نوعی واکسن در بخش تحقیقاتی آکسفورد مورد آزمایش و ارزیابی قرار گرفت تا در صورت تمایل والدین و کارکنان بهداشتی، تجویز همزمان آن با واکسن سه گانه و فلج اطفال عملی گردد.

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 1994

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.32.10.2382-2386.1994